Southern blotting is a molecular technique that is used to detect a specific DNA sequence in genomic DNA digests or cDNA library mRNA sequences. It has found wide applications in biomedical research, forensics, and genetic testing. The technique involves restriction endonuclease digestion of genomic DNA, agarose gel electrophoresis, transfer of DNA fragments to a membrane, hybridization of a specific probe to the target fragment, and detection of hybridized probes. It is commonly used to identify polymorphisms or mutations by analyzing restriction fragment length or hybridization patterns. The global southern blotting market is estimated to be valued at US$ 2.8 Bn in 2023 and is expected to exhibit a CAGR of 6.8% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.
Market Dynamics:
Growing demand for technique in disease diagnosis: Southern blotting technique found widespread application in disease diagnosis. It allows detection of infectious pathogens like viruses, bacteria, and parasites in biological samples. It is also used for identifying genetic abnormalities associated with diseases like cancer. The technique plays a crucial role in prenatal testing and screening for genetic disorders. Thus, growing incidence of chronic and infectious diseases is expected to drive the demand for southern blotting over the forecast period.
Flourishing by demand from biopharmaceutical companies and researchers: Southern blotting technique is extensively used in biopharmaceutical and biotech companies for gene cloning, identification of gene expression patterns, and genetic fingerprinting applications. It is widely adopted by life science researchers for detection of polymorphic sequences, transgenes, and gene rearrangements. Thus, growing R&D investments in drug development and genomic research from biopharma firms and research institutes are expected to support market growth over the forecast period.
Segment Analysis
The Southern Blotting Market is segmented into three segments, namely reagents, kits and instruments. Among these, the reagents segment accounts for the largest market share of around 45% as of 2024. The reagents segment, led by the DNA/RNA probes and markers sub-segment, dominates due to high consumption of consumables including primary/secondary antibodies and probes required on a regular basis for conducting southern blotting techniques. The high recurring demand for reagents keeps this segment ahead of others.
PEST Analysis
Political: The southern blotting market is favored by supportive regulatory environment for new drug discovery and development across regions. However, stringent approval process by regulatory authorities remains a challenge.
Economic: Advancements in molecular biology techniques, growth of pharmaceutical and biotechnology industries, rising prevalence of chronic diseases are driving the economic growth of this market. High cost of equipment and operations poses an obstacle.
Social: Growing awareness about personalized medicines and better diagnosis of genetic diseases has increased the social acceptance of molecular diagnostic technologies like southern blotting.
Technological: Automation and development of advanced detection systems is simplifying the southern blotting process. Digitalized images allow accurate quantification and reduction in workload. Miniaturization of devices is enhancing portability.
Key Takeaways
The Global Southern Blotting Market Size is expected to witness high growth at a CAGR of 6.8% during the forecast period of 2023 to 2030.
Regional analysis: The Asia Pacific region is expected to be the fastest growing market during the forecast period. This can be attributed to increasing research funding, presence of major market players, rising incidence of chronic diseases, growing demand for better diagnostics and emergence of regional players in the region. Countries like China and India are expected to lead the market growth in the Asia Pacific region.
Key players operating in the Southern Blotting Market are Ganeden, Sabinsa Corporation, UAS Laboratories, Sanzyme, Mitsubishi Chemical Foods Corporation, Mystical Biotech Pvt. Ltd., Aumgene Biosciences, Unique Biotech Ltd., Nebraska Culture, and Syngem Biotech. Ganeden and Sabinsa Corporation are recognized as technology leaders in the market owing to their strong product portfolio and global presence.
*Note:
1. Source: Coherent Market Insights, Public sources, Desk research
2. We have leveraged AI tools to mine information and compile it
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