The Advanced Glycation End Products (AGEs) market involves products used in diagnosis and treatment of glycation related diseases. AGEs accumulate during aging and smoking and damage proteins and tissues as they age, contributing to diseases like diabetes, heart disease and kidney disease.
The Global Advanced Glycation End Products Market is estimated to be valued at US$ 130.7 Bn in 2024 and is expected to exhibit a CAGR of 6.1% over the forecast period 2024 to 2031
AGEs are modified proteins or lipids that form as a result of a non-enzymatic reaction between reducing sugars and amino groups on proteins, lipids or nucleic acids. They accumulate with aging and smoking and contribute to inflammation, oxidative stress and cardiovascular complications in conditions like diabetes. AGE inhibitors are used to reduce accumulation of AGEs while AGE breakers breakdown existing cross-links of AGEs to minimize complications. Tests are also available to measure levels of circulating and tissue AGEs to diagnose and monitor glycation related diseases.
Key Takeaways
Key players operating in the Advanced Glycation End Products market are Alteon Inc., Plexxikon Inc., Phenomenome Discoveries Inc., Kowa Company Ltd., Novartis International AG, OPKO Health, Inc., DiabetOmics, Inc., Amadori Scientific, LabCorp, Quest Diagnostics Incorporated, AstraZeneca plc, Bayer AG, Bristol-Myers Squibb Company, Pfizer Inc., GlaxoSmithKline plc, Merck and Co., Inc., Eli Lilly and Company, Sanofi S.A.
The prevalence of Advanced Glycation End Products Market Growth that promote AGE formation and accumulation is a key factor driving increased demand for AGE diagnostics and therapeutics. According to International Diabetes Federation, approximately 537 million adults aged 20-79 years were living with diabetes in 2021 and it is projected to rise to 643 million by 2030 and 783 million by 2045.
Players in the AGE products market are expanding their presence globally with a focus on emerging Asian and Latin American countries where diabetes and chronic kidney disease incidence is rising rapidly due to changing lifestyles and demographics.
Market Key Trends
The increasing interest in anti-aging therapeutics is a major trend in the Advanced Glycation End Products Market Challenges And Opportunities since accumulation of AGEs is associated with aging and age-related conditions. Several novel AGE-crosslink breakers and AGE inhibitor drugs are in clinical trials which if successful, may emerge as new treatment options for various chronic diseases driven by aging. Another key trend involves widespread adoption of AGE reader devices and tests by clinical laboratories for convenient diagnosis and monitoring of diabetes, CKD and other non-alcoholic fatty liver diseases. Developments of sensitive multiplexed assays to simultaneously measure multiple AGE compounds is also gaining attention in research.
Porter’s Analysis
Threat of new entrants: The advanced glycation end products market has moderate barriers for new entrants. Moderate capital requirements and established customers relationships of existing players make market entry challenging for new players.
Bargaining power of buyers: Buyers have moderate bargaining power. Presence of many players and differentiation in products increases options for buyers.
Bargaining power of suppliers: Suppliers have low to moderate bargaining power due to availability of substitutes and differentiated requirements of buyers.
Threat of new substitutes: Threat of substitutes is low as there are limited substitute options for advanced glycation end products.
Competitive rivalry: Market includes many international and regional players leading to high competitive rivalry.
Geographical Regions
North America region accounts for the largest share of the advanced glycation end products market in terms of value due to presence of major players, rising prevalence of chronic diseases and growing awareness.
Asia Pacific region is expected to witness fastest growth during the forecast period owing to growing geriatric population, increasing healthcare expenditures and development of healthcare infrastructure in emerging economies like India and China.
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- *Note:
1. Source: Coherent Market Insights, Public sources, Desk research
2. We have leveraged AI tools to mine information and compile it
About Author – Alice Mutum
Alice Mutum is a seasoned senior content editor at Coherent Market Insights, leveraging extensive expertise gained from her previous role as a content writer. With seven years in content development, Alice masterfully employs SEO best practices and cutting-edge digital marketing strategies to craft high-ranking, impactful content. As an editor, she meticulously ensures flawless grammar and punctuation, precise data accuracy, and perfect alignment with audience needs in every research report. Alice’s dedication to excellence and her strategic approach to content make her an invaluable asset in the world of market insights. LinkedIn